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   Source To Surgery - February 1995, Vol. 3 Issue I

Aeroallergens Contamination in O.R. Environment

Recent studies have demonstrated that glove powder, cornstarch used as a donning agent, is not an allergen per se, but is probably an environmental contaminant which through adsorption of Mutable latex protein carries these allergens through the medical environment.

With the use of large area sampler of Air SentinelTM devise developed by Mark Swanson of Mayo, Dr. Yunginger and colleagues sampled and collected airborne particles in various areas of the operating room and hospital environments. These samplers were programmed to periodically sample air in various geographic work areas of the medical center which had in common a high usage of powdered gloves. The presence of latex was later confirmed by inhibition immunoassays.

Geographic work areas where powdered gloves were used in ug/m3 of aeroallergen:

Urology 122 Dermatology 78
Surgery 100 Blood Bank 46
Orthopedics 100 Venipuncture 30

Geographic work areas with low usage of powdered latex gloves or high usage of synthetic gloves:

Allergy Clinic 1.8 ug/m3
Pulmonary Function .6
Bone Marrow Lab .6

Through the utilization of a personal breathing zone sampler worn by medical personnel throughout the workday, environmental samples were taken. Tagged workers wore these to gain the following average values over an 8-hour workday.

Anesthetists 411 ug/m3
Venipuncture Technicians #1 137
Venipuncture Technicians #2 26
Hematopathlogy Technicians 8

Sampling of the Surgical Suites utilizing personal breathing zone samples were placed in two locations - one on the anesthetists' end of the table and another on the head of the OR table to simulate exposure experienced by the surgical patient.

ug/m3
Room # Air Changes/Hr Anesthetists Table Room
#1 23 974 208 151
#2 23 636 118 88
#3 23 549 96 114
#4 225 * 613 130 92
PostAnesthesia
Recovery Room
2-6 - - 112
* (Orthopedic Specialty Rm)

These measurements describe a wide variety of exposure up to a 4-fold difference at different parts in the same room where the anesthetists receive greater exposure than the patient.

Even the special orthopedic surgical suite with 225 changes of air/hour was insufficient to wash out or dilute the aeroallergens from the air.

Editor's Note: These studies led to the conclusion that if powdered glove use is to be continued only gloves which measure low in allergen content should be used. The complete study published in Journal of Allergy Clinical Immunology Sept. 94 might be useful to readers wishing more details.

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