Professional Healthcare
Understanding Latex Allergy
in the Healthcare Setting


DIAGNOSTIC SCREENING AND ALLERGENICITY TESTING OF GLOVE PRODUCTS


Tests available for the diagnosis of individuals with natural rubber latex and chemical allergy.

ALLERGENICITY TEST METHODS
TEST DEFINITION METHOD INDICATIONS
Patch Test Patch testing determines allergic sensitivity. A suspected allergen is applied to the skin on a small surgical pad for a period of time, indicating whether that substance causes inflammation of the skin. A drop of elutable glove extract or a piece of rubber glove is placed on the client’s forearm. The area is checked in a specified length of time, typically 20 minutes. Assessment for hypersensitivity to both chemical and protein allergens.
Rast Test
(Radioallergosorbent
test)
This IgE blood test looks at the total amount of antibodies. It identifies what types of IgE proteins trigger allergic reactions, signifying that an individual is prone to latex allergy. This method uses a blood sample from a suspected NRL-sensitized individual. It measures specific IgE antibodies against NRL allergens. This method is reported to have an 80% sensitivity and 100% specificity in non-atopic individuals. Quantitative measurement of allergen-specific IgE antibody in the patient’s serum.
Skin Prick
Test (SPT)
A test for latex allergy or sensitivity. This is considered to be the “gold standard” for allergy testing because of its reliability. Elutable proteins are extracted by cutting 1 gram of glove into small pieces and soaking the pieces at room temperature in 5ml of normal saline for 15 minutes. A drop of this solution is placed on the forearm, which is then pierced by a lancet, and the resulting reaction compared to saline as a negative control. Assessment for hypersensitivity to protein allergens.

Would not be used for routine diagnosis of latex hypersensitivity.


Previous Page | Table of Contents | Next Page
Global Gateway Contact Us About Ansell Healthcare Privacy Policy